Use of Recombinant Human Erythropoietin Outside the Setting of Uremia
نویسندگان
چکیده
منابع مشابه
Use of recombinant human erythropoietin outside the setting of uremia.
R concentration. Abnormally high Epo levels have been reported in patients with aplastic anemia, and dramatic ECOMBINANT human erythropoietin (rHuEpo) became available for clinical trials in 1985 and was introduced into clinical practice for correction of anemia of renal changes in serum levels have been described after chemotherapy and during vitamin B12 or iron replacement therfailure in 1989...
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15 صفحه اولThe effect of recombinant human erythropoietin (rHuEpo) on blood cells of adult and immature rats
Human recombinant erythropoietin is a synthetic hormone for treatment of some kinds of anemia. In this study, the effect of this hormone was investigated on blood cell changes in adult and immature rats. For this purpose, the hormone was administered at doses of 50, 100, and 200 IU/Kg (s.c.) twice a week for a period of 6 weeks. Then, the number of red blood cells (RBC), subtypes of white blood...
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Recombinant human erythropoietin is a glycoprotein hormone that stimulates erythropoiesis. In clonogenic assays of hematopoietic progenitors, high concen-trations of erythropoietin (Epo) increase CFU-E and diminish the number of granulocytes formed per culture plate. Fetal progenitors are more sensitive to these effects of Epo than progenitors from adults. We administered doses 50, 100, 200 IU/...
متن کاملGuidelines for the use of recombinant human erythropoietin.
ecombinant human erythropoietin (rHuEpo) is increasingly being used for the treatment of anemia. In view of the unpredictibility of response in most anemic states outside renal failure, the high economic cost, and the high expectation patients and physicians pose in its effect, its clinical use requires expertise and committment. This article was prepared by five experts: four on behalf of the ...
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ژورنال
عنوان ژورنال: Blood
سال: 1997
ISSN: 1528-0020,0006-4971
DOI: 10.1182/blood.v89.12.4248